Cities of refuge were designated to provide protection to unwitting murderers, and it was necessary to clearly mark the roads leading to them. The Sages derive from this the degree to which God accompanies and guides the wicked, and all the more so the righteous.

When Moses stood, the Holy One, Blessed be He, said to him: “You shall designate cities, cities of refuge they shall be for you” (Numbers 35:11). Moses said: Master of the Universe, one who unwittingly kills another in the south or the north, from where will he know where the cities of refuge are so that he can flee there? God said to him: “You shall prepare the way for you” (Deuteronomy 19:3). Direct the path for you so that the one fleeing will not err and the blood redeemer will find him and kill him…. Moses said to Him: How? God said to him: Position signs for them that direct them to the cities of refuge, so he will know how to go there. Write on each sign: Murderer, flee to a city of refuge…Therefore, David said: “Good and upright is the Lord; therefore He instructs sinners in the way” (Psalms 25:8). If for murderers He prepares a path and a way so they can flee and be saved, all the more so for the righteous: “He guides the humble with justice” (Psalms 25:9). (Tanĥuma [Buber], Masei)